Single Nucleotide Polymorphisms: Methods and Protocols
Lisa D. Brooks (auth.), Pui-Yan Kwok MD, PhD (eds.)
Pui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.
ক্যাটাগোরিগুলো:
সাল:
2003
সংস্করণ:
1
প্রকাশক:
Springer New York
ভাষা:
english
পৃষ্ঠা:
283
ISBN 10:
1592593275
ISBN 13:
9781592593279
বইয়ের সিরিজ:
Methods in Molecular Biology 212
ফাইল:
PDF, 3.00 MB
IPFS:
,
english, 2003